Once-A-Day Male Contraceptive Pill Successful In First Clinical Trials

Male contraceptive pill on the horizon

And the latest, a male oral contraceptive called dimethandrolone undecanoate (DMAU), appears to be safe and effective when taken daily for a month.

The new pill is known as DMAU and works similarly to the female birth control pill, using a combination of hormones to lower sperm count below the amount needed for a female to become pregnant, according to US News & World Report.

In a survey, men have answered that they would prefer a contraceptive pill instead of gels and injectable substances.

Page says a second study of DMAU will involve 100 men, 50 in Washington and 50 in California. "Longer term studies are now underway to confirm that DMAU taken every day blocks sperm production", Page said.

For now, even though the Male Contraceptive Initiative has provided a $US150,000 grant for the scientists to move into the next phase of developing the drug, Dr Ventura said how quick the pill is developed and released would depend on more funding. "Despite testosterone levels that were very low, the men had no symptoms", Page said.

A daily pill for males has always been elusive to pharmaceutical developers, as oral testosterone in previous forms may damage the liver or clear the body too quickly to work in just one pill per day. The study authors said there was "marked suppression" of testosterone and of two hormones necessary for a man to produce sperm for those who took 400mg of DMAU, the highest dose.

Subjects took the drug or placebo for 28 days once daily with food. DMAU needs to be taken with food to work properly, the researchers noted.

More news: A 19-year-old College Student Has Gone Missing in Bermuda

The results from the new DMAU study will be presented Sunday March 18 at ENDO 2018, the Endocrine Society's 100th annual meeting in Chicago, Ill.

In a nutshell (sorry, couldn't resist), the pill lowers sperm hormones while not altering testosterone levels.

There was no significant change in mood or sexual function, but a small number of participants experienced decreased libido during the study.

The idea of contraceptive pills for men has been floating about for some time now.

However, many men who took the pill did experience weight gain - about 3 to 8 lbs., on average - during the study, and they saw a drop in their levels of "good" cholesterol. The team have overcome previous problems that assailed developers of male hormonal pills, she believes.

To test DMAU's safety, researchers developed a double-blind randomized, dose escalation, placebo-controlled study. She added the current trial was to determine if the pill could be taken safely for more than one dose, but did not test its effectiveness as a contraceptive.

Related News:

  • Is President Trump Ditching National Security Advisor HR McMaster?

    Is President Trump Ditching National Security Advisor HR McMaster?

    McMaster , who is reported by WaPo to be next on the chopping block, is focused on "big issues", Sanders insisted. "You guys would like us to be focused on" the White House cabinet chaos, but National Security Advisor H.R.
    UMBC's March Madness win earns everyone in US  free pizza

    UMBC's March Madness win earns everyone in US free pizza

    United States pizza franchise Little Caesars may be regretting a promotion it did for the NCAA's March Madness tournament . Since that announcement, the news created Madness all across social media.
    Jets net No. 3 pick in trade with Colts

    Jets net No. 3 pick in trade with Colts

    We can debate the merits of NY yielding three second-round picks in a move up from the sixth pick to No. 3 overall all we want. The only quarterback under contract for more than one year is Christian Hackenberg , and we know he's not the future.
  • Arizona woman, hit by Uber self-driving auto , dies

    Arizona woman, hit by Uber self-driving auto , dies

    The Uber CEO Dara Khosrowshahi also posted a tweet on Monday saying: "Some incredibly sad news out of Arizona ". Researchers and engineers are working on the technology now to try to get it to that level of efficiency.
    Stenson shares lead with DeChambeau at Bay Hill

    Stenson shares lead with DeChambeau at Bay Hill

    Meanwhile the competition sharpened its skills and took aim, adding many birdies to their scorecards while Woods did not. Also competing are Rory McIlroy , Henrik Stenson, Hideki Matsuyama , Bubba Watson, Jason Day and Rickie Fowler .
    Kremlin says response to Britain could come 'any minute'

    Kremlin says response to Britain could come 'any minute'

    Britain has expelled 23 Russian diplomats and suspended high-level contacts with Moscow over the incident. Time and time again, member states say they oppose the use of chemical weapons under any circumstance.
  • Tottenham Hotspur to face Manchester United in FA Cup semi-finals

    Tottenham Hotspur to face Manchester United in FA Cup semi-finals

    Both semis will be at Wembley, Tottenham's temporary home for this season, on the weekend of April 21-22. Tottenham got through courtesy of two Christian Eriksen goals in a 3-0 win over Swansea .
    37th annual St. Patrick's Day parade in downtown Rockford

    37th annual St. Patrick's Day parade in downtown Rockford

    Police said those arrests were city-wide, which includes the South Side, North Side, downtown, and other areas. Irish Prime Minister Leo Varadkar tak es part in the 2018 Saint Patricks Day Parade today in New York City.
    Kasatkina beats Williams; Osaka ousts Halep at Indian Wells

    Kasatkina beats Williams; Osaka ousts Halep at Indian Wells

    The Swiss maestro missed the last six months of the 2016 campaign due to a knee injury and returned for the 2017 Australian Open. Coric held steadily throughout the first set and broke Federer's serve in the eleventh game and held for to close out the set.
  • Katy Perry just gave Taylor Swift the biggest backhanded compliment

    Katy Perry just gave Taylor Swift the biggest backhanded compliment

    She then went on Carpool Karaoke and declared that it was Swift's job to finish their fight because she started it. She kept silent while Perry went on a press tour for " Swish Swish " and her album " Witness ".
    Fire at Manila hotel kills at least 3 workers

    Fire at Manila hotel kills at least 3 workers

    The fire was raised to Task Force Bravo as of 1 pm on Sunday, based on updates from the ground. Maria Orosa Avenue and UN Avenue were closed to traffic due to the thick smoke in the area.
    Chelsea fullback Alonso: We were unlucky - but they have Messi

    Chelsea fullback Alonso: We were unlucky - but they have Messi

    I think it is better to wait until the end of the season. "I will do my best for it", he told Standard Sport . 'Obviously there is no extension signed but I don't think now is the moment to do it.


Most liked

Ex-Wolves assistant Musselman rips off shirt after Nevada makes Sweet 16
Vincent Edwards scored 20 points despite early foul trouble for Purdue, and Matt Haarms filled in capably for the injured Haas. The Spartans (30-5) made just 25.8 percent of their field-goal attempts as their frustration mounted against Syracuse's zone.

Trump has banned Venezuelan cryptocurrency in the US
Venezuelan President Nicolas Maduro said each Petro token would be backed by one barrel of the state's oil. Marco Rubio (R., Fla.) applauded Monday's action against Venezuela .

Cynthia Nixon announces her run for governor of NY
After weeks of hinting that she would seek the Democratic nomination for governor of New York, Cynthia Nixon has made it official. The lifelong New Yorker has been politically active in recent years. "I've never lived anywhere else", Nixon says in the video .

Trump pushes drug-dealer death penalty as opioid crisis response
Trump has declared that fighting the epidemic is a priority for the administration, but critics say the effort has fallen short. Flake told New Hampshire Republicans that someone needs to stop Trump - and it could be him if no one else steps up.

Spring begins Tuesday; a little snow possible Wednesday
Plan for hard travel conditions, especially during the evening commute on Wednesday with possible reductions in visibility. Winds will peak on Wednesday , with gusts to 40+ miles per hour across interior NJ and 50+ miles per hour along the coast.

Ukraine will not allow Russians to vote at Russian consulates - interior minister
Russia said the vote repaired a historical wrong after the historically Russian region was handed over to Ukraine 60 years ago. Nauert blasted the 2014 referendum in Crimea as to whether the region should join Russian Federation .

Corker predicts Trump will pull out of Iran nuclear deal
His stance and position with Trump could give Pompeo leverage with the Europeans that Tillerson never enjoyed. But if he eggs on Trump's most belligerent instincts, I believe the Iran deal won't last the year.

Trump Lawyers Want To Take The Stormy Case Federal
One of the reasons she cited is that Trump, who went by the alias David Dennison in the nondisclosure pact, did not sign it. Cohen has not explained why he made the payment and has not said if Trump was aware of it.

Israeli soldiers killed in West Bank auto attack
Israel's Shin Bet security service said he had spent time in prison for security offenses and was released past year . He also rejected the Hamas terror group's statement of praise for the attack.

Xi Jinping unanimously elected Chinese president,
On Saturday, a key Xi ally, Wang Qishan, was appointed to the previously ceremonial post of vice president. Mr Lee also wrote to Mr Li Keqiang to congratulate him on his re-appointment as the Chinese Premier.

Florida State advances past Missouri, 67-54
The Tigers also needed to stay out of foul trouble, a lesson learned in Missouri's 62-60 loss to Georgia in the SEC Tournament. Porter is considered a likely lottery pick, possibly even top five for the National Basketball Association draft in June.

Nordic athlete Arendz to be Canada's flagbearer at Paralympic closing ceremony
Masters' five-medal haul in Pyeongchang has increased her Paralympic count to eight between Nordic skiing and rowing. Similar to her first run in snowboard cross, Coury, 31, fell in her first run Friday, but she shook off the spill.

Check your mail! Fortnite iOS invites are going out right now
First Drake and Travis Scott played the game on Twitch , and now Fortnite has finally been released on Apple's iOS platform. Many fans will need to free up some storage space to play the game, although it's definitely worth it.

TDP moves its own no confidence. It is a damage control exercise
Odisha's Biju Janata Dal also backed the southern parties and extended its support to the no-confidence motion. I took the decision, not for selfish reasons, but for interests of Andhra Pradesh.

Dozens Said Killed In Separate Attacks In Syria's Ghouta, Afrin
Syrians believe they can distinguish Russian aircraft from those of the Syrian army because the Russians fly at higher altitude. The assault on eastern Ghouta has devastated towns across the region and damaged and destroyed over a dozen hospitals.